Brittleness tester---FRV3000

Based on the earliest Roche design principles, it gradually became the standard in the pharmaceutical industry, used to test the ability of tablets to resist vibration and wear during production, packaging, and transportation, such as peeling, debris, wear, and even rupture caused by compression; While ensuring the principle remains unchanged, continuous improvement has been made to ensure the reliability and ease of operation of the system, formingFRandFRVSeries.

To meet your usage requirements,CopleyThe company can provide three different types of documents and certificates.

Compliant with the United States/Certificate of European Pharmacopoeia:Each instrument is provided with this certificate for free, ensuring that the product complies with the requirements of the pharmacopoeia standards from design to production

Laser coding and certification:When analyzing and identifying drugs as unqualified, certification documents that meet the corresponding pharmacopoeia technical requirements must be provided, and this certificate is optional.

IQ/OQ/PQCertification documents:The complete set of documents guides users to install, operate equipment, and perform performance testing under their experimental conditions, providing comprehensive records of completing analysis tasks and archiving them.

Strictly following the methods of the United States Pharmacopeia and other pharmacopoeias,FRThe rotation speed of the series is fixed at25RPMThere are two models: one with a detection round drumFR1000And two round drumsFR2000，FRVSeries andFVSimilar, the difference is that the speed can be adjusted:20-60RPMThe advantage of variable rotational speed is that the operator can analyze the impact of different force conditions on the tablet, thereby determining the optimal tablet shape. allFRAll series can choose the number of rotations of the round drum（1-999999）Or operating time（99hour59divide59During operation, in secondsLCDThe screen displays the number of cycles or time that have been run and the remaining cycles and time, as well as the rotational speed.

The circular drum of the brittleness tester is designed to detect the durability of the rotation and collision of tablets. It has a running curve: first let the tablet rise, then fall down, and its distance is156mmPremature exceptions and edge detachment indicate that the tablet cannot withstand strict transportation requirements; All round drums have a gap, so there is no need to remove or open them when loading and pouring out samples. At the beginning of the analysis, the circular drum automatically rotates the gap in front of the operator for easy loading of samples. After completing the detection, the circular drum automatically stops and instead automatically pours the sample into the collection tray. All circular drums can be interchanged and installed on either side of the instrument. You can choose a wear drum for measuring wear detection, with a diameter of20cmIt brings the pills to a predetermined height and slides them, allowing them to constantly rub against each other. All hosts can be equipped with either a brittleness round drum or a wear round drum that complies with the United States Pharmacopeia. The dual drum instrument can be equipped with one brittleness round drum and one wear round drum, enabling comparison of two parameters under the same analysis conditions.

After selecting the method that includes running cycles and time, simply press“START”The analysis can be initiated, and the standard testing process is: take10Weighing of tablet drugs（W1）If a single drug is smaller than650Milligram, ensure that the total weight is within6.5Weigh about grams and remove dust before weighing. Then put it into the round drum and let it rotate100Next, weigh again after removing the dustW2So calculate the percentage of weight loss=（W1-W2）/W1*100Under normal circumstances, the maximum loss of the total weight of the drug cannot exceed1%If necessary, take the middle two of the three analyses.